SCHEMBL21113700

SCHEMBL21113700

CC(=O)c1cccc(/C(C)=N\c2ccc3ccccc3n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.46
CSNK1G2 P78368 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
MAP4K5 Q9Y4K4 1/20 0.46
CNR2 P34972 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 4/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
PDE10A Q9Y233 1/20 0.40
GAA P10253 1/20 0.40
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24404252 0.78 PLAU (0.51) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
SCHEMBL21113672 0.75 KMT2A (0.50) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
SCHEMBL24404253 0.75 KMT2A (0.50) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
SCHEMBL21113701 0.75 KMT2A (0.41) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
SCHEMBL21113691 0.72 KMT2A (0.49) ALDH1A1MAPTHPGDKMT2ANPC1
SCHEMBL24404284 0.72 KMT2A (0.49) ALDH1A1MAPTHPGDKMT2ANPC1
SCHEMBL7120291 0.69 MAPT (0.59) ALDH1A1MAPTKMT2ANPC1RAB9A
SCHEMBL279656 0.69 ALDH1A1 (0.59) ALDH1A1KMT2ANPC1RAB9AMEN1
SCHEMBL10764144 0.69 CYSLTR2 (0.64) ALDH1A1MAPTKMT2ANPC1RAB9A
SCHEMBL21113670 0.69 MEN1 (0.50) MAP4K4CSNK1G2CLK4MKNK2MAP4K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US disclosed