Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114675 | 0.84 | CTSD (0.45) | KCNK3KCNK9ALDH1A1TSHRRXFP1 | |
| SCHEMBL20981405 | 0.82 | IRAK4 (0.58) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL21114605 | 0.80 | HCRTR1 (0.49) | KCNK3KCNK9ALDH1A1TSHRKDM4E | |
| SCHEMBL21114678 | 0.78 | PRSS1 (0.39) | IRAK4ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL28293902 | 0.78 | IRAK4 (0.70) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL21114590 | 0.78 | IRAK4 (0.57) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL3261086 | 0.77 | IRAK4 (0.59) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL21114705 | 0.74 | IRAK4 (0.46) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL20981426 | 0.73 | IRAK4 (0.51) | IRAK4KCNK3KCNK9IDO1TDO2 | |
| SCHEMBL21114681 | 0.73 | IRAK4 (0.48) | IRAK4KCNK3KCNK9IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954361-B2 | Curing agent for silicone rubber compounds | NITROCHEMIE ASCHAU GMBH (DE) | 2021-03-23 | — | — | US | claimed |
| EP-3484897-B1 | HARDENER FOR SILICONE RUBBER MASSES | NITROCHEMIE GMBH (DE) | 2020-12-23 | — | — | EP | claimed |
| EP-3484970-B1 | COMPOSITION FOR SILICONE RUBBER MASSES | NITROCHEMIE GMBH (DE) | 2020-07-08 | — | — | EP | claimed |
| US-20190211187-A1 | CURING AGENT FOR SILICONE RUBBER COMPOUNDS | NITROCHEMIE ASCHAU GMBH (DE) | 2019-07-11 | — | — | US | claimed |
| EP-3841167-B1 | COMPOSITION FOR SILICONE RUBBER MASSES | NITROCHEMIE GMBH (DE) | 2023-02-22 | — | — | EP | disclosed |
| US-20210324195-A1 | Composition for Silicone Rubber Masses | NITROCHEMIE ASCHAU GMBH (DE) | 2021-10-21 | — | — | US | disclosed |
| US-10954361-B2 | Curing agent for silicone rubber compounds | NITROCHEMIE ASCHAU GMBH (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20190211187-A1 | CURING AGENT FOR SILICONE RUBBER COMPOUNDS | NITROCHEMIE ASCHAU GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10954361-B2 | Curing agent for silicone rubber compounds | CARM1, PRMT1, SRRM2 | IRAK4 519/4885KCNK3 3101/4885KCNK9 2717/4885 |
| US-20190211187-A1 | CURING AGENT FOR SILICONE RUBBER COMPOUNDS | CARM1, PRMT1, SRRM2 | IRAK4 519/4885KCNK3 3101/4885KCNK9 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.