Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 1.00 |
| ▸ | HTT | P42858 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.79 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.79 |
| ▸ | CTSB | P07858 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | IDO1 | P14902 | 2/20 | 0.78 |
| ▸ | TDO2 | P48775 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521547 | 0.88 | ALDH1A1 (1.00) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8164006 | 0.88 | MAPT (1.00) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL18300579 | 0.88 | MAPT (1.00) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL24716142 | 0.84 | KDM4E (0.72) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7960630 | 0.83 | MAPT (0.79) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27190082 | 0.82 | MAPT (1.00) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27190087 | 0.82 | KDM4E (0.78) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL17597346 | 0.82 | KMT2A (0.70) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL24716103 | 0.82 | MAPT (0.78) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27190064 | 0.82 | MAPT (0.78) | MAPTKDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265677-B1 | CORROSION DETECTION PRODUCT AND METHOD | BATTELLE MEMORIAL INSTITUTE (US) | 2019-05-15 | — | — | EP | claimed |
| EP-4623914-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| EP-4537825-A1 | USE OF NITROXOLINE COMPOUND IN ENHANCING EFFECT OF ANTIBACTERIAL AGENT | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| CN-118843464-A | Application of nitrooxyquinoline compound in enhancing antibacterial agent effect | 江苏亚虹医药科技股份有限公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| EP-4349815-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| CN-117224542-A | Application of nitrooxyquinoline compound in enhancing antibacterial agent effect | 江苏亚虹医药科技股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023236893-A1 | USE OF NITROXOLINE COMPOUND IN ENHANCING EFFECT OF ANTIBACTERIAL AGENT | 江苏亚虹医药科技股份有限公司 | 2023-12-14 | — | — | WO | disclosed |
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |
| WO-2007068316-A1 | HYDROXYQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |
| US-20070099970-A1 | Immunomodulatory compounds that target and inhibit the pY'binding site of tyrosene kinase p56 LCK SH2 domain | UNIVERSITY OF MARYLAND, BALTIMORE | 2007-05-03 | — | — | US | disclosed |
| EP-0327052-A2 | Use of quinoline derivatives for making a medicament effective in the prevention and treatment of ulcers | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4831040-A | (IMIDAZOLO-, THIAZOLO-, OXAZOLO-)(4,5-H)-QUINOLINE | RORER PHARMACEUTICAL CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0090360-B1 | NEW QUINOLINE AND RELATED COMPOUNDS USEFUL AS ANTI-ALLERGY AGENTS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4698346-A | Thiazolo[5,4-h]quinoline compounds useful as anti-allergy agents | USV PHARMACEUTICAL CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| US-4656281-A | Imidazo quinoline compounds useful as anti-allergy agents | USV PHARMACEUTICAL CORP. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4563463-A | ASTHMA | USV PHARMACEUTICAL CORP. (US) | 1986-01-07 | — | — | US | disclosed |
| US-4522947-A | Certain 1,3-oxazolo[4,5H]quinolines useful as anti-allergy agents | USV PHARMACEUTICAL CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0090360-A2 | New quinoline and related compounds useful as anti-allergy agents | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099970-A1 | Immunomodulatory compounds that target and inhibit the pY'binding site of tyrosene kinase p56 LCK SH2 domain | LCK, PTPN6, PTPN22 | MAPT 2522/4885KDM4E 1518/4885MEN1 4192/4885 |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | CYP3A7, UGT1A7, UGT2B7 | MAPT 4416/4885KDM4E 2921/4885MEN1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.