SCHEMBL21115577

SCHEMBL21115577

C=C(C)C(=O)OCCCc1cc(-c2ccc(-c3ccccc3)cc2C2CC2)cc(CCCOC(=O)C(=C)C)c1OCCC(CO)(CO)CCCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
SLC6A9 P48067 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21098038 0.91 CNR1 (0.34) CNR1CNR2
SCHEMBL21064936 0.90 P2RY14 (0.30)
SCHEMBL21097821 0.90 P2RY14 (0.30)
SCHEMBL21115667 0.90 TSHR (0.33) CNR1CNR2NR1H2NR1H3TSHR
SCHEMBL21115764 0.89 S1PR1 (0.33) NR1H2NR1H3TSHR
SCHEMBL21115966 0.88 IDO1 (0.33) CNR1CNR2TSHR
SCHEMBL21675387 0.88 TSHR (0.37) CNR1CNR2NR1H2NR1H3TSHR
SCHEMBL21098044 0.88 CNR1 (0.33) CNR1CNR2
SCHEMBL21115673 0.88 TSHR (0.35) CNR1CNR2NR1H2NR1H3TSHR
SCHEMBL21115630 0.88 TSHR (0.34) CNR1CNR2NR1H2NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3502209-B1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2020-10-14 EP disclosed
EP-3502209-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2019-06-26 EP disclosed