Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159115 | 0.95 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21693411 | 0.92 | POLB (0.32) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559830 | 0.91 | POLB (0.41) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL16559845 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22592280 | 0.89 | ELANE (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18476361 | 0.89 | ELANE (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559831 | 0.89 | POLB (0.39) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18511710 | 0.87 | NR4A2 (0.39) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL19914777 | 0.87 | POLB (0.37) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL22353022 | 0.86 | POLB (0.37) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720925-B1 | WINDOW ELEMENT | MERCK PATENT GMBH (DE) | 2023-02-15 | — | — | EP | disclosed |
| EP-3604481-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |
| EP-3235894-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-3504292-B1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3502210-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |