Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21115722 | 0.95 | POLB (0.37) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL16559830 | 0.93 | POLB (0.41) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL16559845 | 0.92 | POLB (0.40) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL16559831 | 0.91 | POLB (0.39) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL24170586 | 0.90 | THRB (0.35) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL18487314 | 0.90 | THRB (0.35) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL18820263 | 0.89 | POLB (0.33) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL18511710 | 0.89 | NR4A2 (0.39) | POLBAPEX1HTTTDP1AAK1 | |
| SCHEMBL25795454 | 0.88 | POLB (0.36) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL19159161 | 0.88 | NR4A2 (0.38) | POLBAPEX1HTTTDP1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |