Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18779753 | 0.83 | OPRD1 (0.41) | OPRD1OPRK1OPRM1GRIN2B | |
| SCHEMBL1950165 | 0.73 | OPRM1 (0.44) | OPRD1OPRK1OPRM1GRIN2B | |
| SCHEMBL20902460 | 0.71 | OPRD1 (0.36) | OPRD1OPRK1OPRM1GRIN2BTMEM97 | |
| SCHEMBL1953079 | 0.67 | DRD1 (0.39) | OPRD1OPRK1OPRM1GRIN2BTMEM97 | |
| SCHEMBL24591822 | 0.67 | POLA1 (0.36) | OPRD1OPRK1OPRM1 | |
| SCHEMBL21570050 | 0.66 | POLA1 (0.38) | OPRD1OPRK1OPRM1GRIN2BTMEM97 | |
| SCHEMBL13538862 | 0.66 | PDK2 (0.38) | OPRD1OPRK1 | |
| SCHEMBL13538865 | 0.66 | PDK2 (0.38) | OPRD1OPRK1 | |
| SCHEMBL1951446 | 0.66 | GRIN2B (0.37) | OPRD1OPRK1OPRM1GRIN2B | |
| SCHEMBL23715381 | 0.66 | OPRD1 (0.44) | OPRD1OPRK1OPRM1GRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074379-B1 | OPIOID AGONISTS AND USES THEREOF | NEKTAR THERAPEUTICS INDIA PVT LTD (IN) | 2019-06-26 | — | — | EP | disclosed |