Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23981527 | 0.95 | CAMKK2 (0.41) | CAMKK2ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL5728643 | 0.78 | PTGDR2 (0.51) | CAMKK2GAAMAPTKDM4ECRBN | |
| SCHEMBL5297499 | 0.77 | MAPT (0.44) | CAMKK2ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL16423721 | 0.77 | MAPT (0.53) | CAMKK2ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL30313698 | 0.77 | MAPT (0.44) | CAMKK2ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL6910638 | 0.76 | PTGDR2 (0.50) | ALDH1A1KDM4EMEN1KMT2ACYP2C19 | |
| SCHEMBL14686745 | 0.75 | GAA (0.58) | ALDH1A1GAAMAPTKDM4ECRBN | |
| SCHEMBL5509735 | 0.75 | PDK2 (0.41) | ALDH1A1GAAMAPTKDM4ECYP3A4 | |
| SCHEMBL7534043 | 0.75 | CHRNA1 (0.42) | CAMKK2MAPTKDM4ECAMKK1MEN1 | |
| SCHEMBL17681983 | 0.75 | CYP2D6 (0.43) | ALDH1A1CRBNMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074379-B1 | OPIOID AGONISTS AND USES THEREOF | NEKTAR THERAPEUTICS INDIA PVT LTD (IN) | 2019-06-26 | — | — | EP | disclosed |