SCHEMBL21116459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21116545	1.00	AR (0.38)	ARIMPDH2PDE9APDE1CBCHE
	SCHEMBL21116327	0.93	AR (0.42)	ARBCHEACHEKDM4EALDH1A1
	SCHEMBL21116543	0.92	AR (0.38)	ARIMPDH2PDE9APDE1CKDM4E
	SCHEMBL21116544	0.92	AR (0.38)	ARIMPDH2PDE9APDE1CKDM4E
	SCHEMBL24926840	0.92	PDE9A (0.39)	ARIMPDH2PDE9APDE1CBCHE
	SCHEMBL21116334	0.91	AR (0.47)	ARIMPDH2KDM4EALDH1A1MAPT
	SCHEMBL21116552	0.89	AR (0.38)	ARIMPDH2PDE9APDE1CKDM4E
	SCHEMBL22519649	0.89	IMPDH2 (0.41)	IMPDH2PDE9APDE1CBCHEACHE
	SCHEMBL25513040	0.89	IMPDH2 (0.41)	IMPDH2PDE9APDE1CBCHEACHE
	SCHEMBL19062273	0.89	KDM4E (0.42)	ARIMPDH2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.