⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115865 | 0.76 | ALDH1A1 (0.61) | — | |
| SCHEMBL10872877 | 0.76 | — | — | |
| SCHEMBL1754710 | 0.76 | ALDH1A1 (0.61) | — | |
| SCHEMBL5338908 | 0.74 | — | — | |
| SCHEMBL131895 | 0.73 | — | — | |
| SCHEMBL12558160 | 0.73 | — | — | |
| SCHEMBL29445 | 0.73 | — | — | |
| SCHEMBL14776464 | 0.73 | ALDH1A1 (0.57) | — | |
| SCHEMBL4906704 | 0.73 | CYP2C9 (0.69) | — | |
| SCHEMBL4961560 | 0.73 | CYP2C9 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39707-E1 | Camptothecin derivatives | CATHOLIC HEALTHCARE WEST (US) | 2007-06-26 | — | — | US | claimed |
| EP-1383772-B1 | NITROGEN-BASED CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MED CENTER (US) | 2006-08-30 | — | — | EP | claimed |
| US-6350756-B1 | USEFUL FOR TREATING CANCER; (20S) ESTERS WITH AN OXYALKANOIC ACID; | CALIFORNIA PACIFIC MEDICAL CENTER | 2002-02-26 | — | — | US | claimed |
| US-8158809-B2 | Podophyllotoxin derivatives | SUTTER WEST BAY HOSPITALS (US) | 2012-04-17 | — | — | US | disclosed |
| US-7632954-B2 | Sym-N-(n-hexyl)-5-bromotriindole; Sym-N-(n-hexyl)-5-phenyltriindole; Sym-N-(n-hexyl)-[2-cyano-2-(4-pyridyl)vinyl]triindole; electrification preventions, electrification controls, capacitors, batteries, chemical sensors, displays, organic EL materials, solar cells, photodiodes, phototransistors; fibers | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20090298870-A1 | PODOPHYLLOTOXIN DERIVATIVES | Sutter West Bay Hospitals, dba California Pacific Medical Center and Catholic Healthcare West | 2009-12-03 | — | — | US | disclosed |
| US-7605262-B2 | Podophyllotoxin derivatives | SUTTER WEST BAY HOSPITALS (US) | 2009-10-20 | — | — | US | disclosed |
| US-7497970-B2 | Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal | FUJIFILM CORPORATION (JP) | 2009-03-03 | — | — | US | disclosed |
| US-20080113941-A1 | Podophyllotoxin Derivatives | CALIFORNIA PACIFIC MEDICAL CENTER | 2008-05-15 | — | — | US | disclosed |
| EP-1020760-B1 | Heat developable image recording material | FUJIFILM CORP (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20070228325-A1 | Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal | FUJIFILM CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| US-6342689-B1 | CONVEYING RECORDING MATERIAL AND SLIDING OVER SURFACE OF BOTTOM HEATER, THERMALLY PROCESSING BOTH SIDES OF MATERIAL BY PRESSING PART OF MATERIAL DURING CONVEYANCE AGAINST SURFACE OF BOTTOM HEATER AND HEATING FROM BOTH TOP AND BOTTOM HEATERS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-01-29 | — | — | US | disclosed |
| US-6261754-B1 | DIMENSIONAL STABILITY; PROTECTIVE COATING OF POLYMER IN BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-6159654-A | Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-1045284-A1 | Heat developing method for heat developable image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1041434-A1 | Heat-developable photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-1020760-A2 | Heat developable image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |