⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872877 | 0.78 | — | — | |
| SCHEMBL1754710 | 0.78 | ALDH1A1 (0.61) | — | |
| SCHEMBL2115865 | 0.78 | ALDH1A1 (0.61) | — | |
| SCHEMBL12558160 | 0.74 | — | — | |
| SCHEMBL2111775 | 0.74 | — | — | |
| SCHEMBL4961560 | 0.74 | CYP2C9 (0.69) | — | |
| SCHEMBL29445 | 0.74 | — | — | |
| SCHEMBL14776464 | 0.74 | ALDH1A1 (0.57) | — | |
| SCHEMBL4906704 | 0.74 | CYP2C9 (0.69) | — | |
| SCHEMBL2755215 | 0.74 | CYP2C9 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836180-A2 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | sanofi-aventis (FR) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006072393-A2 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI-AVENTIS (DE) | 2006-07-13 | — | — | WO | disclosed |