SCHEMBL21118964

SCHEMBL21118964

CCN1C(=O)/C(=C\c2ccc(N(c3ccccc3)C3C=CC=CC3)cc2)OC1=S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
ALOX15 P16050 1/20 0.50
HPGD P15428 1/20 0.47
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
GPR35 Q9HC97 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.33
IDE P14735 1/20 0.33
HSD17B3 P37058 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CYBB P04839 1/20 0.33
NOX4 Q9NPH5 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12320112 0.92 MEN1 (0.40) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL2622700 0.82 MEN1 (0.64) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL17970069 0.80 MEN1 (0.34) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL13893205 0.79 MEN1 (0.35) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL14564537 0.79 MAPT (0.35) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL15382593 0.79 MAPT (0.35) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL12014039 0.74 MEN1 (0.57) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL13009272 0.72 RELA (0.38) ALDH1A1MEN1KMT2AHPGDSMN1; SMN2
SCHEMBL1104316 0.71 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AALOX15HPGD
SCHEMBL12013793 0.71 MEN1 (0.51) ALDH1A1MEN1KMT2AALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102709-B1 PIGMENT-DISPERSED COMPOSITION, CURABLE COMPOSITION, COLOR FILTER AND PRODUCTION METHOD THEREOF FUJIFILM CORP (JP) 2019-06-26 EP disclosed