Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21119500 | 1.00 | CYP2C19 (0.56) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL8199716 | 0.84 | HDAC3 (0.47) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL14926310 | 0.84 | HDAC1 (0.47) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL3719792 | 0.81 | CYP2C19 (0.64) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL14678141 | 0.81 | CYP1A2 (0.49) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL10982127 | 0.80 | KCNN4 (0.58) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL21119498 | 0.79 | HDAC3 (0.43) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL31172766 | 0.78 | CYP2C19 (0.60) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL4870717 | 0.76 | CYP2C19 (0.61) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL13270940 | 0.75 | MAPT (0.57) | CYP2C19HIF1AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | ELOVL5, FASN, ACSL5 | CYP2C19 1453/4885HIF1A 2470/4885HDAC3 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.