Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138820 | 0.91 | CYP2C19 (0.52) | CYP2C19HIF1AKMT2ACYP1A2CYP2D6 | |
| SCHEMBL28435577 | 0.89 | HIF1A (0.52) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL31172766 | 0.84 | CYP2C19 (0.60) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL10972965 | 0.82 | CYP2C19 (0.44) | CYP2C19HIF1AMAPTKMT2ACYP2D6 | |
| SCHEMBL27484429 | 0.82 | HIF1A (0.48) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL10982127 | 0.82 | KCNN4 (0.58) | CYP2C19HIF1AMAPTKMT2ATSHR | |
| SCHEMBL4949586 | 0.82 | CYP2C19 (0.48) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL4870717 | 0.82 | CYP2C19 (0.61) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL21119499 | 0.81 | CYP2C19 (0.56) | CYP2C19HIF1AMAPTKMT2ACYP1A2 | |
| SCHEMBL21119500 | 0.81 | CYP2C19 (0.56) | CYP2C19HIF1AMAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567225-A | Method for preparing dicarboxylic acid compound from olefin | 徐州医科大学 | 2024-02-20 | — | — | CN | disclosed |
| US-10947231-B2 | Processes for the preparation of substituted tetrahydro beta-carbolines | PTC THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| CN-110028403-B | Method for synthesizing succinic acid compound | 四川大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-110028403-A | A kind of method of synthesizing succinic acid class compound | 四川大学 | 2019-07-19 | — | — | CN | disclosed |
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS INC (US) | 2019-05-09 | — | — | US | disclosed |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS, INC. | 2012-05-31 | — | — | US | disclosed |
| CN-102459263-A | Process for the preparation of substituted tetrahydro beta-carbolines | PTC THERAPEUTICS INC | 2012-05-16 | — | — | CN | disclosed |
| WO-2010138644-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
| EP-1268581-B1 | STABLE INITIATOR SYSTEM | JOHNSON & JOHNSON VISION CARE (US) | 2004-11-24 | — | — | EP | disclosed |
| US-6720079-B2 | THERMOSETTING POWDER COMPOSITION INCLUDING EPOXIDE CROSSLINKER AND POLYESTER HAVING TERMINAL TERTIARY CARBOXYL GROUPS FORMED BY REACTING PREPOLYESTER WITH COMPOUND HAVING TERTIARY CARBOXYL GROUP AND ANOTHER CARBOXYL GROUP OR HYDROXYL GROUP | UCB, S.A. (BE) | 2004-04-13 | — | — | US | disclosed |
| WO-2001070824-A2 | STABLE INITIATOR SYSTEM | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0302516-B1 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-5075488-A | Fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0128006-B1 | A SOIL-DISEASE-CONTROLLING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4910291-A | From aromatic diacid | MITSUBISHI RAYON COMPANY LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0302516-A2 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO., LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |
| US-4709052-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| EP-0028430-B1 | A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
| EP-0028430-A1 | A process for the electroreductive preparation of organic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947231-B2 | Processes for the preparation of substituted tetrahydro beta-carbolines | TPH1, TPH2, HTR1B | CYP2C19 69/4885HIF1A 2638/4885MAPT 1457/4885 |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | CYP2C19 59/4885HIF1A 2740/4885MAPT 1428/4885 |
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | CYP2C19 69/4885HIF1A 2638/4885MAPT 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.