⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2111399 | 0.92 | — | — | |
| SCHEMBL2111320 | 0.90 | ENPEP (0.37) | — | |
| SCHEMBL2111307 | 0.90 | ENPEP (0.37) | — | |
| SCHEMBL10944752 | 0.83 | — | — | |
| SCHEMBL11054393 | 0.83 | — | — | |
| SCHEMBL10940176 | 0.83 | — | — | |
| SCHEMBL8835084 | 0.76 | — | — | |
| SCHEMBL555027 | 0.76 | — | — | |
| SCHEMBL42855 | 0.74 | — | — | |
| SCHEMBL19066807 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158587-B2 | Compound having histone deacetylase-inhibiting activity, and pharmaceutical composition comprising the compound as an active ingredient | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090275728-A1 | COMPOUND HAVING HISTONE DEACETYLASE-INHIBITING ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND AS AN ACTIVE INGREDIENT | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2009-11-05 | — | — | US | disclosed |