Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2111320 | 1.00 | ENPEP (0.37) | ENPEPFOLH1 | |
| SCHEMBL2111399 | 0.98 | — | — | |
| SCHEMBL2111984 | 0.90 | — | — | |
| SCHEMBL11054393 | 0.84 | — | — | |
| SCHEMBL10944752 | 0.79 | — | — | |
| SCHEMBL10940176 | 0.79 | — | — | |
| SCHEMBL381494 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL1664514 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL2111197 | 0.76 | — | — | |
| SCHEMBL3326811 | 0.76 | OPRM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158587-B2 | Compound having histone deacetylase-inhibiting activity, and pharmaceutical composition comprising the compound as an active ingredient | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090275728-A1 | COMPOUND HAVING HISTONE DEACETYLASE-INHIBITING ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND AS AN ACTIVE INGREDIENT | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275728-A1 | COMPOUND HAVING HISTONE DEACETYLASE-INHIBITING ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND AS AN ACTIVE INGREDIENT | HDAC1, HDAC11, HDAC3 | ENPEP 328/4885FOLH1 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.