SCHEMBL21119988

SCHEMBL21119988

c1ccc2cc3c(-c4ccc5ccc6cccnc6c5n4)ccc(-c4ccc5c(ccc6c7ccccc7sc56)c4)c3cc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
CLK2 P49760 1/20 0.34
HIPK1 Q86Z02 1/20 0.34
DYRK2 Q92630 1/20 0.34
HIPK2 Q9H2X6 1/20 0.34
HIPK3 Q9H422 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
CCR1 P32246 4/20 0.33
CCR8 P51685 4/20 0.33
LMNA P02545 3/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CCR5 P51681 2/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MMP2 P08253 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21120229 0.97 ALOX5 (0.38) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL21119914 0.94 ALOX5 (0.42) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL24695387 0.93 ALOX5 (0.35) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL21119598 0.91 ALOX5 (0.39) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL21119680 0.87 LMNA (0.38) ALOX5CCR1CCR8LMNAMAPT
SCHEMBL21119583 0.87 CCR1 (0.36) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL21119845 0.87 LMNA (0.33) CLK2HIPK1DYRK2HIPK2HIPK3
SCHEMBL21119854 0.86 ALOX5 (0.39) ALOX5CLK2HIPK1DYRK2HIPK2
SCHEMBL21119576 0.85 CCR1 (0.35) ALOX5CCR1CCR8LMNAMAPT
SCHEMBL21119768 0.83 CCR1 (0.33) ALOX5CCR1CCR8LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522139-B2 Organic light emitting diode LG DISPLAY CO., LTD. (KR) 2022-12-06 US disclosed
US-20190207123-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2019-07-04 US disclosed