Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 14/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664156 | 0.82 | S1PR3 (0.61) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL23715829 | 0.77 | S1PR3 (0.44) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL23716004 | 0.75 | S1PR3 (0.62) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL23715866 | 0.73 | S1PR3 (0.71) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL23715868 | 0.73 | S1PR3 (0.58) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL17664134 | 0.69 | S1PR3 (0.85) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL28736369 | 0.69 | LMNA (0.55) | S1PR3S1PR1NPC1RAB9AALDH1A1 | |
| SCHEMBL17664399 | 0.68 | S1PR3 (0.91) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL23716172 | 0.68 | S1PR3 (0.71) | S1PR3S1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL17663946 | 0.67 | S1PR3 (0.80) | S1PR3S1PR1S1PR4S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323029-B2 | Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323029-B2 | Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders | S1PR1, SPHK1, S1PR3 | S1PR3 3/4885S1PR1 1/4885S1PR4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.