Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779015 | 0.93 | MEN1 (0.44) | SIGMAR1MEN1EBP | |
| SCHEMBL17778834 | 0.85 | MEN1 (0.45) | SIGMAR1MEN1EBP | |
| SCHEMBL17779021 | 0.85 | CASP6 (0.43) | SIGMAR1MEN1EBP | |
| SCHEMBL21130823 | 0.83 | SIGMAR1 (0.52) | SIGMAR1MEN1EBP | |
| SCHEMBL17779016 | 0.82 | MEN1 (0.43) | SIGMAR1MEN1EBP | |
| SCHEMBL17768498 | 0.81 | SIGMAR1 (0.43) | SIGMAR1MEN1EBP | |
| SCHEMBL17779017 | 0.81 | CHRM2 (0.46) | SIGMAR1MEN1EBP | |
| SCHEMBL17778831 | 0.81 | SIGMAR1 (0.47) | SIGMAR1MEN1EBP | |
| SCHEMBL19564578 | 0.80 | MAPK1 (0.43) | SIGMAR1MEN1 | |
| SCHEMBL17778822 | 0.80 | SIGMAR1 (0.42) | SIGMAR1MEN1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221314-B1 | SPIRO-ISOQUINOLINE-1,4'-PIPERIDINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-07-03 | — | — | EP | disclosed |