Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326627 | 0.75 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL79660 | 0.75 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12188761 | 0.74 | MAPT (0.43) | MAPT | |
| SCHEMBL12790540 | 0.73 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27274508 | 0.73 | FDPS (0.39) | — | |
| SCHEMBL13417410 | 0.73 | FDPS (0.39) | — | |
| SCHEMBL2058214 | 0.73 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1TSHR | |
| Water SCHEMBL3302021 | 0.73 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21793424 | 0.72 | MAPT (0.31) | MAPTMEN1KMT2A | |
| SCHEMBL11787058 | 0.72 | MAPT (0.35) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185413-A1 | BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF | QUADRIGA BIOSCIENCES, INC. | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185413-A1 | BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF | SLC3A2, SLC7A1, SLC43A1 | MAPT 1800/4885MEN1 3165/4885KMT2A 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.