Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20020537 | 0.76 | NPY5R (0.53) | — | |
| SCHEMBL22010639 | 0.76 | NPY5R (0.53) | — | |
| SCHEMBL5139794 | 0.69 | RAB9A (0.65) | — | |
| Hydrochloric Acid SCHEMBL27440821 | 0.68 | RAB9A (0.64) | — | |
| SCHEMBL27488421 | 0.68 | RAB9A (0.63) | — | |
| SCHEMBL29500941 | 0.68 | AVPR1A (0.73) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL29500702 | 0.68 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL28449068 | 0.67 | AVPR1A (0.80) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL28449067 | 0.67 | AVPR1A (0.80) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL29500594 | 0.67 | AVPR1A (0.80) | AVPR1AAVPR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019116325-A1 | TRICYCLIC COMPOUNDS AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2019-06-20 | — | — | WO | disclosed |