Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.59 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325278 | 0.79 | NAMPT (0.53) | NAMPTLMNA | |
| SCHEMBL21132523 | 0.79 | NAMPT (0.53) | NAMPT | |
| SCHEMBL21324571 | 0.77 | PKM (0.55) | NAMPTLMNA | |
| SCHEMBL21132840 | 0.77 | NAMPT (0.55) | NAMPT | |
| SCHEMBL30927202 | 0.75 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379252 | 0.75 | NAMPT (1.00) | NAMPT | |
| SCHEMBL21324567 | 0.74 | NAMPT (0.54) | NAMPT | |
| SCHEMBL21324855 | 0.74 | GHSR (0.42) | NAMPTLMNA | |
| SCHEMBL21132795 | 0.74 | NAMPT (0.55) | NAMPTLMNA | |
| SCHEMBL21324818 | 0.74 | NAMPT (0.38) | NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329275-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329275-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNT, NQO1 | NAMPT 1/4885GPR17 1672/4885LMNA 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.