SCHEMBL21132977

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@H](F)[C@H]1OP(=O)(O)OC[C@@H]1C[C@@H](F)[C@H](n2cnc3c(N)ncnc32)O1

nearest known ligand 0.69

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	12/20	0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22571183	0.94	RNASEL (0.60)	RNASEL
SCHEMBL21417366	0.88	P2RY1 (0.66)	RNASEL
SCHEMBL20324919	0.88	P2RY1 (0.66)	RNASEL
SCHEMBL20224844	0.88	P2RY1 (0.66)	RNASEL
SCHEMBL20326922	0.88	P2RY1 (0.66)	RNASEL
SCHEMBL22080502	0.88	RNASEL (0.57)	RNASEL
SCHEMBL21133320	0.87	P2RX3 (0.56)	RNASEL
SCHEMBL22930677	0.86	RNASEL (0.51)	RNASEL
SCHEMBL24181933	0.86	RNASEL (0.55)	RNASEL
SCHEMBL22080515	0.86	RNASEL (0.56)	RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3505527-A1	CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION	Invivogen (FR)	2019-07-03	—	—	EP	disclosed