Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 6/20 | 0.53 |
| ▸ | RXRB | P28702 | 5/20 | 0.53 |
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | RARG | P13631 | 4/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688872 | 0.96 | RXRA (0.53) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL21133286 | 0.96 | EGFR (0.58) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL20026783 | 0.96 | EGFR (0.58) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL18624975 | 0.96 | EGFR (0.58) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL5668225 | 0.93 | EGFR (0.61) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL30872343 | 0.92 | RARB (0.56) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL15521781 | 0.92 | RARB (0.56) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL22972758 | 0.89 | DHODH (0.49) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL17354676 | 0.89 | DHODH (0.49) | EGFRRXRARXRBRARBRARG | |
| SCHEMBL17014858 | 0.87 | RARB (0.51) | EGFRRARBRARGPTPN11RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210106973-A1 | Metal Organic Frameworks for Gas Storage | UNIV KING ABDULLAH SCI & TECH (SA) | 2021-04-15 | — | — | US | disclosed |
| US-10870101-B2 | Metal organic frameworks for gas storage | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2020-12-22 | — | — | US | disclosed |
| US-20190255511-A1 | Metal Organic Frameworks for Gas Storage | UNIV KING ABDULLAH SCI & TECH (SA) | 2019-08-22 | — | — | US | disclosed |
| US-10322402-B2 | Metal organic frameworks for gas storage | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2019-06-18 | — | — | US | disclosed |