Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263796 | 0.99 | TDP1 (0.35) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL24179920 | 0.89 | TDP1 (0.32) | TDP1 | |
| SCHEMBL6947345 | 0.85 | ALDH1A1 (0.41) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL16664312 | 0.85 | ALDH1A1 (0.41) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL18095075 | 0.84 | ALDH1A1 (0.38) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL19263751 | 0.83 | MEN1 (0.33) | TSHR | |
| SCHEMBL24179933 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL19263668 | 0.82 | — | — | |
| SCHEMBL21133584 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL19263653 | 0.81 | USP2 (0.34) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659591-B1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3549963-B1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | KODIAK SCIENCES INC (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3659591-A1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-2558538-B1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | KODIAK SCIENCES INC (US) | 2019-07-03 | — | — | EP | disclosed |