Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16664312 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL18095075 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL14713388 | 0.91 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL19881242 | 0.90 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL14713399 | 0.89 | THRB (0.35) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL12640739 | 0.89 | THRB (0.35) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL14713286 | 0.87 | POLB (0.33) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL21133635 | 0.85 | TDP1 (0.35) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL14713292 | 0.85 | POLB (0.34) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL29781936 | 0.85 | THRB (0.33) | ALDH1A1TSHRTP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653415-B1 | Atom transfer radical polymerization (ATRP) by reaction with initiator | BOETTCHER HENRIK (DE) | 2003-11-25 | — | — | US | disclosed |
| EP-1124857-B1 | METHOD FOR PRODUCING DEFINED LAYERS OR LAYER SYSTEMS | BOETTCHER HENRIK (DE) | 2003-04-09 | — | — | EP | disclosed |