SCHEMBL21133869

SCHEMBL21133869

CC(=O)c1c(I)c(I)c(C(=O)O)c(I)c1I

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
CYP3A4 P08684 2/20 0.33
TPMT P51580 1/20 0.33
THRB P10828 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
HTT P42858 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16342093 0.86 LMNA (0.34) LMNACYP3A4TPMTTHRBMEN1
SCHEMBL22680939 0.85 CYP3A4 (0.38) LMNACYP3A4THRBMEN1HPGD
SCHEMBL7596897 0.85 TPMT (0.41) LMNATPMTMEN1HPGDKMT2A
SCHEMBL28857244 0.84 LMNA (0.33) LMNACYP3A4TPMTTHRBMEN1
SCHEMBL3830951 0.84 LMNA (0.34) LMNAHPGDKMT2AKDM4EALDH1A1
SCHEMBL9600105 0.82 TPMT (0.39) LMNATPMTCYP1A2CA12CA1
SCHEMBL8855992 0.82 TPMT (0.39) LMNATPMTCYP1A2CA12CA1
SCHEMBL1859003 0.82 TPMT (0.39) LMNATPMTCYP1A2CA12CA1
Hydrochloric Acid SCHEMBL8541347 0.82 TPMT (0.39) LMNATPMTCYP1A2CA12CA1
Hydrochloric Acid SCHEMBL8824728 0.79 TPMT (0.38) LMNATPMTCYP1A2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10342232-B1 Iodinated polymers for biological agent defeat THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10342232-B1 Iodinated polymers for biological agent defeat TBCA, HSP90AB2P, LRBA LMNA 4808/4885CYP3A4 4384/4885TPMT 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.