SCHEMBL8855992

SCHEMBL8855992

O=C(O)c1c(I)c(I)c(C(=O)O)c(I)c1I.[KH].[KH]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.39
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
DPP4 P27487 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9600105 1.00 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
SCHEMBL7596897 0.96 TPMT (0.41) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL8541347 0.93 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
SCHEMBL1859003 0.93 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
SCHEMBL8537633 0.90 TPMT (0.38) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL8824728 0.90 TPMT (0.38) TPMTCYP1A2LMNACA12CA1
SCHEMBL4587818 0.89 TPMT (0.41) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL8536294 0.87 TPMT (0.36) TPMTCYP1A2LMNACA12CA1
SCHEMBL4265757 0.86 TPMT (0.39) TPMTCYP1A2LMNACA12CA1
Hydrochloric Acid SCHEMBL9787611 0.86 TPMT (0.39) TPMTCYP1A2LMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693321-A Polymers containing diester units NYCOMED IMAGING AS (NO) 1997-12-02 US disclosed
US-5534250-A METHYLENE DIESTER GROUPS, BIODEGRADABLE NYCOMED IMAGING AS (NO) 1996-07-09 US disclosed
EP-0547126-B1 BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS NYCOMED IMAGING AS (NO) 1996-02-28 EP disclosed