Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.37 |
| ▸ | ADH1A | P07327 | 4/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | ADH7 | P40394 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639368 | 0.87 | ADH1B (0.38) | ADH1BADH1AADH1CADH7KMT2A | |
| SCHEMBL6338704 | 0.77 | — | — | |
| SCHEMBL19559437 | 0.77 | — | — | |
| SCHEMBL25106080 | 0.72 | HPGDS (0.32) | HPGDS | |
| SCHEMBL25106076 | 0.72 | HPGDS (0.32) | HPGDS | |
| SCHEMBL24777625 | 0.72 | HPGDS (0.32) | HPGDS | |
| SCHEMBL9963368 | 0.72 | MAPK1 (0.36) | HPGDS | |
| SCHEMBL23270649 | 0.72 | IDH1 (0.35) | HPGDS | |
| SCHEMBL14601915 | 0.72 | MAPK1 (0.32) | HPGDS | |
| SCHEMBL6385322 | 0.71 | HPGDS (0.41) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47493-E1 | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-07-09 | — | — | US | disclosed |