Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DNM1L | O00429 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135203 | 0.85 | ATR (0.45) | ATRPIK3CAMTORCNR2NAPEPLD | |
| SCHEMBL21055102 | 0.81 | KDM4E (0.51) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL21055507 | 0.78 | ATR (0.52) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL30312386 | 0.78 | ATR (0.52) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL30312517 | 0.77 | KDM4E (0.49) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL21055026 | 0.77 | KDM4E (0.49) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL21055011 | 0.77 | LMNA (0.51) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL30312410 | 0.77 | LMNA (0.51) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL21135504 | 0.77 | LMNA (0.51) | ATRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL30312523 | 0.77 | LMNA (0.51) | ATRALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |