Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135205 | 0.85 | ATR (0.53) | ATRCNR2NAPEPLDKDM4ENPC1 | |
| SCHEMBL21055063 | 0.83 | KDM4E (0.49) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL30312464 | 0.83 | KDM4E (0.49) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL21135207 | 0.71 | ATR (0.41) | ATRNAPEPLDKDM4ENPC1MAPT | |
| SCHEMBL30312542 | 0.70 | ATR (0.49) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL21055086 | 0.70 | ATR (0.49) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL30312523 | 0.70 | LMNA (0.51) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL21055011 | 0.70 | LMNA (0.51) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL30312509 | 0.70 | PIKFYVE (0.50) | ATRKDM4EMAPTIRAK4 | |
| SCHEMBL21135271 | 0.70 | LMNA (0.50) | ATRCNR2KDM4EMAPTIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |