Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.40 |
| ▸ | MTOR | P42345 | 7/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135265 | 0.88 | PIKFYVE (0.41) | PIKFYVEMTORPIK3CAPIK3R1PIK3CB | |
| SCHEMBL30312455 | 0.82 | PIKFYVE (0.64) | PIKFYVEMTORPIK3CAPIK3CBGAA | |
| SCHEMBL23272116 | 0.82 | PIKFYVE (0.64) | PIKFYVEMTORPIK3CAPIK3CBGAA | |
| SCHEMBL24710650 | 0.79 | MTOR (0.39) | MTORPIK3CAPIK3R1PIK3CBGAA | |
| SCHEMBL1856157 | 0.78 | SMN1; SMN2 (0.46) | MTORPIK3CAPIK3R1PIK3CBGAA | |
| SCHEMBL21135266 | 0.78 | PIKFYVE (0.41) | PIKFYVEMTORPIK3CAPIK3R1PIK3CB | |
| SCHEMBL23804706 | 0.78 | KDM4E (0.42) | MTORPIK3CAPIK3R1PIK3CBGAA | |
| SCHEMBL25172897 | 0.76 | GRK6 (0.40) | MTORPIK3CAPIK3R1PIK3CBGAA | |
| SCHEMBL23815273 | 0.76 | PIK3CA (0.38) | MTORPIK3CAPIK3R1PIK3CBGAA | |
| SCHEMBL30369885 | 0.76 | GRK6 (0.40) | MTORPIK3CAPIK3R1PIK3CBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |