Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 8/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135264 | 0.88 | PIKFYVE (0.40) | PIKFYVEPIK3CBHSD17B10ALDH1A1TP53 | |
| SCHEMBL23272140 | 0.83 | PIKFYVE (0.64) | PIKFYVEPIK3CBMTORPIK3CALMNA | |
| SCHEMBL30312313 | 0.83 | PIKFYVE (0.64) | PIKFYVEPIK3CBMTORPIK3CALMNA | |
| SCHEMBL23815493 | 0.78 | LMNA (0.43) | PIK3CBHSD17B10ALDH1A1TP53CYP1A2 | |
| SCHEMBL21135266 | 0.77 | PIKFYVE (0.41) | PIKFYVEPIK3CBMTORPIK3CAPIK3R1 | |
| SCHEMBL21135267 | 0.75 | PIKFYVE (0.40) | PIKFYVEPIK3CBHSD17B10ALDH1A1TP53 | |
| SCHEMBL21135268 | 0.73 | PIKFYVE (0.40) | PIKFYVEPIK3CBMTORPIK3CAPIK3R1 | |
| SCHEMBL23272116 | 0.72 | PIKFYVE (0.64) | PIKFYVEPIK3CBMTORPIK3CALMNA | |
| SCHEMBL23272139 | 0.72 | PIKFYVE (0.64) | PIKFYVEPIK3CBMTORPIK3CALMNA | |
| SCHEMBL30312455 | 0.72 | PIKFYVE (0.64) | PIKFYVEPIK3CBMTORPIK3CALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |