Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.41 |
| ▸ | MTOR | P42345 | 8/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135267 | 0.95 | PIKFYVE (0.40) | PIKFYVEMTORPIK3CAPIK3CDPARP1 | |
| SCHEMBL21135268 | 0.93 | PIKFYVE (0.40) | PIKFYVEMTORPIK3CAPIK3CDPARP1 | |
| SCHEMBL23272139 | 0.84 | PIKFYVE (0.64) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL30312341 | 0.84 | PIKFYVE (0.64) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL21135828 | 0.81 | PIKFYVE (0.54) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL30312396 | 0.80 | PIKFYVE (0.61) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL23272130 | 0.80 | PIKFYVE (0.61) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL23272115 | 0.79 | PIKFYVE (0.59) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL30312358 | 0.79 | PIKFYVE (0.59) | PIKFYVEMTORPIK3CAPIK3CDPIK3CB | |
| SCHEMBL21135264 | 0.78 | PIKFYVE (0.40) | PIKFYVEMTORPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |