Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135266 | 0.95 | PIKFYVE (0.41) | PIKFYVEKMT2AMAPTMTORPIK3CA | |
| SCHEMBL21135268 | 0.91 | PIKFYVE (0.40) | PIKFYVEKMT2AMAPTMTORPIK3CA | |
| SCHEMBL23272130 | 0.85 | PIKFYVE (0.61) | PIKFYVEKMT2AMAPTHPGDMTOR | |
| SCHEMBL30312396 | 0.85 | PIKFYVE (0.61) | PIKFYVEKMT2AMAPTHPGDMTOR | |
| SCHEMBL21135841 | 0.82 | PIKFYVE (0.52) | PIKFYVEMAPTHPGDTSHRHTT | |
| SCHEMBL23272139 | 0.80 | PIKFYVE (0.64) | PIKFYVEMEN1KMT2AMAPTHPGD | |
| SCHEMBL30312341 | 0.80 | PIKFYVE (0.64) | PIKFYVEMEN1KMT2AMAPTHPGD | |
| SCHEMBL23804677 | 0.79 | NPC1 (0.44) | MEN1KMT2AMAPTHPGDTSHR | |
| SCHEMBL23815518 | 0.78 | NPY5R (0.44) | MEN1KMT2AMAPTHPGDTSHR | |
| SCHEMBL21135828 | 0.77 | PIKFYVE (0.54) | PIKFYVEMAPTHPGDMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |