Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 7/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.52 |
| ▸ | MTOR | P42345 | 4/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135841 | 0.95 | PIKFYVE (0.52) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL21135835 | 0.94 | PIKFYVE (0.53) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL23272104 | 0.84 | PIKFYVE (0.76) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL30312501 | 0.84 | PIKFYVE (0.76) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL21135266 | 0.81 | PIKFYVE (0.41) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL23272145 | 0.81 | PIKFYVE (0.73) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL30312357 | 0.81 | PIKFYVE (0.73) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL23272105 | 0.79 | PIKFYVE (0.74) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL30312352 | 0.79 | PIKFYVE (0.74) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD | |
| SCHEMBL21135267 | 0.77 | PIKFYVE (0.40) | PIKFYVEPIK3CAPIK3R1MTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |