Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 10/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135404 | 0.92 | PIK3R1 (0.51) | MAPTMTORPIK3CAPIK3R1SETD2 | |
| SCHEMBL21135270 | 0.89 | PTPN11 (0.47) | MTORPIK3CAPIK3R1SETD2PIK3CD | |
| SCHEMBL21135294 | 0.82 | MAPT (0.44) | MAPTMTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL21135486 | 0.81 | PIK3CD (0.41) | PIKFYVEMTORPIK3CAPIK3R1SETD2 | |
| SCHEMBL21135783 | 0.80 | PIK3CD (0.46) | MTORPIK3CAPIK3R1SETD2PIK3CD | |
| SCHEMBL21135407 | 0.80 | PIK3CD (0.44) | PIKFYVEMTORPIK3CAPIK3R1SETD2 | |
| SCHEMBL21135300 | 0.80 | PIKFYVE (0.44) | PIKFYVEMTORPIK3CAPIK3R1SETD2 | |
| SCHEMBL30312401 | 0.80 | PIKFYVE (0.73) | MAPTPIKFYVEMTORPIK3CASETD2 | |
| SCHEMBL21054252 | 0.80 | PIKFYVE (0.73) | MAPTPIKFYVEMTORPIK3CASETD2 | |
| SCHEMBL21135409 | 0.80 | PIK3CD (0.47) | SETD2PIK3CDGRIA1HTTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |