Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 10/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.51 |
| ▸ | MTOR | P42345 | 10/20 | 0.51 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135293 | 0.92 | MAPT (0.46) | PIK3R1PIK3CAMTORSETD2STAT3 | |
| SCHEMBL21135270 | 0.90 | PTPN11 (0.47) | PIK3R1PIK3CAMTORSETD2 | |
| SCHEMBL21135295 | 0.82 | STAT3 (0.50) | PIK3R1PIK3CAMTORSTAT3KDM4E | |
| SCHEMBL21135486 | 0.82 | PIK3CD (0.41) | PIK3R1PIK3CAMTORSETD2STAT3 | |
| SCHEMBL21135300 | 0.81 | PIKFYVE (0.44) | PIK3R1PIK3CAMTORSETD2STAT3 | |
| SCHEMBL21135407 | 0.81 | PIK3CD (0.44) | PIK3R1PIK3CAMTORSETD2STAT3 | |
| SCHEMBL21135783 | 0.81 | PIK3CD (0.46) | PIK3R1PIK3CAMTORSETD2STAT3 | |
| SCHEMBL21135409 | 0.80 | PIK3CD (0.47) | SETD2STAT3NPY5RALDH1A1LMNA | |
| SCHEMBL21054269 | 0.80 | PIKFYVE (0.64) | PIK3R1PIK3CAMTORSETD2KDM4E | |
| SCHEMBL30312535 | 0.80 | PIKFYVE (0.64) | PIK3R1PIK3CAMTORSETD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |