Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135783 | 0.98 | PIK3CD (0.46) | PIK3CDCNR2SETD2STAT3GRIA1 | |
| SCHEMBL21135409 | 0.97 | PIK3CD (0.47) | PIK3CDCNR2SETD2STAT3GRIA1 | |
| SCHEMBL21135486 | 0.95 | PIK3CD (0.41) | PIK3CDCNR2SETD2STAT3GRIA1 | |
| SCHEMBL21135499 | 0.93 | FLT3 (0.41) | PIK3CDCNR2SETD2STAT3GRIA1 | |
| SCHEMBL21135300 | 0.91 | PIKFYVE (0.44) | PIK3CDCNR2SETD2STAT3PIK3R1 | |
| SCHEMBL21135404 | 0.81 | PIK3R1 (0.51) | SETD2STAT3PIK3R1PIK3CAMTOR | |
| SCHEMBL21135293 | 0.80 | MAPT (0.46) | PIK3CDSETD2STAT3GRIA1PIK3R1 | |
| SCHEMBL30312534 | 0.79 | PIKFYVE (0.63) | PIK3CDSETD2PIK3CAMTORGAA | |
| SCHEMBL21135489 | 0.78 | PIK3CD (0.64) | PIK3CDCNR2STAT3PIK3R1 | |
| SCHEMBL21135270 | 0.78 | PTPN11 (0.47) | PIK3CDSETD2PIK3R1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |