Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12683464 | 0.87 | GPR119 (0.46) | MAP4K4CHRM4PANK3KDM4EALDH1A1 | |
| SCHEMBL24038794 | 0.86 | DPP4 (0.47) | CHRM4PANK3KDM4EALDH1A1GPR119 | |
| SCHEMBL30090305 | 0.86 | DPP4 (0.47) | CHRM4PANK3KDM4EALDH1A1GPR119 | |
| SCHEMBL2225620 | 0.84 | USP30 (0.49) | CHRM4PANK3GPR119DPP4DPP8 | |
| SCHEMBL29462081 | 0.83 | RET (0.48) | CHRM4PANK3KDM4EALDH1A1GPR119 | |
| SCHEMBL18787362 | 0.81 | HCRTR1 (0.46) | MAP4K4CHRM4KDM4EALDH1A1POLB | |
| SCHEMBL21135741 | 0.80 | PDE10A (0.56) | MAP4K4POLBGPR119FPR1FPR2 | |
| SCHEMBL15034199 | 0.80 | PDE10A (0.56) | MAP4K4PIK3CAMTORPOLBGPR119 | |
| SCHEMBL2224211 | 0.80 | MAP4K4 (0.50) | MAP4K4KDM4EALDH1A1GPR119SMO | |
| SCHEMBL21135569 | 0.80 | MEN1 (0.47) | MAP4K4PIK3CAMTORKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371196-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PLATELET AGGREGATION | UNIV MONTREAL (CA) | 2021-10-27 | — | — | EP | disclosed |
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | UNIVERSITE DE MONTREAL (CA) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | F12, F2, F3 | MAP4K4 1927/4885PIK3CA 785/4885MTOR 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.