Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | NEK4 | P51957 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135833 | 0.92 | PIKFYVE (0.47) | PIKFYVEPDE7ACNR2RAB9AKMT2A | |
| SCHEMBL21135829 | 0.90 | PIKFYVE (0.48) | PIKFYVEPDE7AMAPK1CNR2 | |
| SCHEMBL21055003 | 0.86 | PIKFYVE (0.68) | PIKFYVEFLT3KMT2A | |
| SCHEMBL30312402 | 0.86 | PIKFYVE (0.68) | PIKFYVEFLT3KMT2A | |
| SCHEMBL30312479 | 0.82 | PIKFYVE (0.71) | PIKFYVEFLT3KMT2A | |
| SCHEMBL21054976 | 0.82 | PIKFYVE (0.71) | PIKFYVEFLT3KMT2A | |
| SCHEMBL30312425 | 0.80 | PIKFYVE (0.68) | PIKFYVEPDE7AKMT2A | |
| SCHEMBL21053987 | 0.80 | PIKFYVE (0.68) | PIKFYVEPDE7AKMT2A | |
| SCHEMBL21055859 | 0.80 | PIKFYVE (0.68) | PIKFYVEPDE7AKMT2A | |
| SCHEMBL23272110 | 0.79 | PIKFYVE (0.67) | PIKFYVERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |