Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 6/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135817 | 0.92 | PIKFYVE (0.49) | PIKFYVECNR2PDE7ARAB9AKMT2A | |
| SCHEMBL21135829 | 0.92 | PIKFYVE (0.48) | PIKFYVECNR2PDE7AALDH1A1LMNA | |
| SCHEMBL23272110 | 0.86 | PIKFYVE (0.67) | PIKFYVERAB9AKMT2ALMNA | |
| SCHEMBL30312400 | 0.86 | PIKFYVE (0.67) | PIKFYVERAB9AKMT2ALMNA | |
| SCHEMBL21054004 | 0.84 | PIKFYVE (0.67) | PIKFYVERAB9AKMT2ANPC1RXFP1 | |
| SCHEMBL30312413 | 0.84 | PIKFYVE (0.67) | PIKFYVERAB9AKMT2ANPC1RXFP1 | |
| SCHEMBL30312346 | 0.83 | PIKFYVE (0.66) | PIKFYVEPDE7ARAB9AKMT2ANPC1 | |
| SCHEMBL21054951 | 0.83 | PIKFYVE (0.66) | PIKFYVEPDE7ARAB9AKMT2ANPC1 | |
| SCHEMBL21053987 | 0.82 | PIKFYVE (0.68) | PIKFYVEPDE7AKMT2ALMNA | |
| SCHEMBL30312425 | 0.82 | PIKFYVE (0.68) | PIKFYVEPDE7AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |