Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 8/20 | 0.48 |
| ▸ | MTOR | P42345 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135833 | 0.92 | PIKFYVE (0.47) | PIKFYVEPDE7AALDH1A1LMNACNR2 | |
| SCHEMBL21135817 | 0.90 | PIKFYVE (0.49) | PIKFYVEPDE7AMAPK1CNR2 | |
| SCHEMBL23272112 | 0.85 | PIKFYVE (0.68) | PIKFYVEMTORPIK3CAKDM4ELMNA | |
| SCHEMBL30312397 | 0.85 | PIKFYVE (0.68) | PIKFYVEMTORPIK3CAKDM4ELMNA | |
| SCHEMBL21054205 | 0.80 | PIKFYVE (0.65) | PIKFYVEMTORPIK3CAPDE7AKDM4E | |
| SCHEMBL30312403 | 0.80 | PIKFYVE (0.65) | PIKFYVEMTORPIK3CAPDE7AKDM4E | |
| SCHEMBL30312425 | 0.80 | PIKFYVE (0.68) | PIKFYVEMTORPIK3CAPDE7AKDM4E | |
| SCHEMBL21053987 | 0.80 | PIKFYVE (0.68) | PIKFYVEMTORPIK3CAPDE7AKDM4E | |
| SCHEMBL21055859 | 0.79 | PIKFYVE (0.68) | PIKFYVEMTORPIK3CAPDE7AKDM4E | |
| SCHEMBL21054004 | 0.78 | PIKFYVE (0.67) | PIKFYVEMTORPIK3CAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |