Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135844 | 0.87 | PIK3CA (0.42) | PIK3CAPIK3CDPIK3R1PIK3CBPIK3CG | |
| SCHEMBL30312344 | 0.85 | PIKFYVE (0.56) | PIK3CAPIK3CDPIK3CBMAPK14LCK | |
| SCHEMBL23272119 | 0.85 | PIKFYVE (0.56) | PIK3CAPIK3CDPIK3CBMAPK14LCK | |
| SCHEMBL21135798 | 0.85 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3R1PIK3CBPIK3CG | |
| SCHEMBL21135799 | 0.84 | PIK3CA (0.42) | PIK3CAPIK3CDPIK3R1PIK3CBPIK3CG | |
| SCHEMBL21055518 | 0.83 | PIKFYVE (0.56) | PIK3CAPIK3CDPIK3CBMAPK14LCK | |
| SCHEMBL21054923 | 0.82 | PIKFYVE (0.55) | PIK3CAPIK3CDPIK3CBMAPK14PIKFYVE | |
| SCHEMBL30312431 | 0.82 | PIKFYVE (0.55) | PIK3CAPIK3CDPIK3CBMAPK14PIKFYVE | |
| SCHEMBL21054281 | 0.82 | PIKFYVE (0.55) | PIK3CAPIK3CDPIK3CBMAPK14LCK | |
| SCHEMBL30312522 | 0.82 | PIKFYVE (0.55) | PIK3CAPIK3CDPIK3CBMAPK14LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |