Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 5/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135797 | 0.94 | PIK3CD (0.39) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21135844 | 0.90 | PIK3CA (0.42) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21135799 | 0.87 | PIK3CA (0.42) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21135831 | 0.85 | PIK3CA (0.42) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21055523 | 0.84 | PIKFYVE (0.54) | PIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL30312320 | 0.84 | PIKFYVE (0.54) | PIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL23272151 | 0.79 | PIKFYVE (0.51) | PIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL30312332 | 0.79 | PIKFYVE (0.51) | PIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL21135843 | 0.77 | PIKFYVE (0.43) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL30312317 | 0.75 | PIKFYVE (0.56) | PIK3CAPIK3CBPIK3CDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |