Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135844 | 0.89 | PIK3CA (0.42) | PIK3CAPIK3CBPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL21135798 | 0.87 | PIK3CA (0.41) | PIK3CAALDH1A1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21054267 | 0.84 | PIKFYVE (0.53) | PIK3CAPIK3CBPIK3CDLMNAMTOR | |
| SCHEMBL30312319 | 0.84 | PIKFYVE (0.53) | PIK3CAPIK3CBPIK3CDLMNAMTOR | |
| SCHEMBL21135831 | 0.84 | PIK3CA (0.42) | PIK3CACYP2C19PIK3CBPIK3CDPIK3CG | |
| SCHEMBL21135797 | 0.83 | PIK3CD (0.39) | PIK3CAPIK3CBPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL16611805 | 0.74 | PIK3CA (0.54) | PIK3CAHSD17B10ALDH1A1TP53CYP1A2 | |
| SCHEMBL21135843 | 0.74 | PIKFYVE (0.43) | PIK3CAPIK3CBPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL21054262 | 0.74 | PIKFYVE (0.56) | PIK3CAPIK3CBPIK3CDLMNAMTOR | |
| SCHEMBL30312395 | 0.74 | PIKFYVE (0.58) | PIK3CAPIK3CBPIK3CDLMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |