Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135846 | 0.95 | PIKFYVE (0.43) | PIKFYVEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21135832 | 0.94 | PIKFYVE (0.42) | PIKFYVEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23272103 | 0.82 | PIKFYVE (0.69) | PIKFYVEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30312514 | 0.82 | PIKFYVE (0.69) | PIKFYVEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23272118 | 0.78 | PIKFYVE (0.66) | PIKFYVEKDM4EHPGDGAAMTOR | |
| SCHEMBL30312416 | 0.78 | PIKFYVE (0.66) | PIKFYVEKDM4EHPGDGAAMTOR | |
| SCHEMBL23272123 | 0.77 | PIKFYVE (0.65) | PIKFYVEKDM4EHPGDGAAMTOR | |
| SCHEMBL30312348 | 0.77 | PIKFYVE (0.65) | PIKFYVEKDM4EHPGDGAAMTOR | |
| SCHEMBL21135833 | 0.76 | PIKFYVE (0.47) | PIKFYVEALDH1A1NPC1RAB9AHTT | |
| SCHEMBL21135829 | 0.75 | PIKFYVE (0.48) | PIKFYVEKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |