Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CD38 | P28907 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018390 | 0.85 | CD38 (0.43) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL31064406 | 0.80 | HTT (0.55) | HTTMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL1642074 | 0.78 | CD38 (0.52) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL138386 | 0.78 | CA2 (0.42) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL14405515 | 0.78 | SLC6A2 (0.43) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL145819 | 0.78 | SLC6A2 (0.40) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL488856 | 0.78 | SLC6A2 (0.40) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL2776951 | 0.78 | STIM1 (0.42) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL2703427 | 0.78 | TAAR1 (0.42) | CD38CYP3A4KCNH2STIM1ORAI1 | |
| SCHEMBL5407429 | 0.78 | SLC6A2 (0.43) | CD38CYP3A4KCNH2STIM1ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377426-B2 | Processes to produce elagolix | SUZHOU PENGXU PHARMATECH CO., LTD. (CN) | 2022-07-05 | — | — | US | disclosed |
| US-20210214318-A1 | PROCESSES TO PRODUCE ELAGOLIX | SUZHOU PENGXU PHARMATECH CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| WO-2019112968-A1 | PROCESSES TO PRODUCE ELAGOLIX | WANG PENG (US) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214318-A1 | PROCESSES TO PRODUCE ELAGOLIX | ELAVL1, ELOB, ELOVL3 | HTT 767/4885CD38 2630/4885CYP3A4 1948/4885 |
| US-11377426-B2 | Processes to produce elagolix | ELAVL1, ELOB, ELOVL3 | HTT 767/4885CD38 2630/4885CYP3A4 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.