SCHEMBL21136845

SCHEMBL21136845

CC1CC(C)(C)C12CCOC(=O)N2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2560263 0.69
SCHEMBL21101299 0.67 LMNA (0.38) LMNACYP2C9
SCHEMBL19526372 0.63
SCHEMBL12681055 0.63 LMNA (0.34) LMNACYP2C9
SCHEMBL29348832 0.62
SCHEMBL2561850 0.62 CRBN (0.30)
SCHEMBL14650880 0.61 LMNA (0.31) LMNACYP2C9
SCHEMBL21101221 0.60
SCHEMBL29348864 0.59
SCHEMBL26112210 0.58 MGLL (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019113173-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2019-06-13 WO disclosed