Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539326 | 0.81 | PPARG (0.46) | HPGDEPHX2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL22561261 | 0.79 | FAAH (0.53) | HPGDEPHX2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL24390753 | 0.77 | SELP (0.46) | HPGDEPHX2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL22561413 | 0.75 | CYP1A2 (0.50) | HPGDEPHX2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL22040693 | 0.75 | HDAC3 (0.52) | CYP1A2CYP2C9SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6344936 | 0.75 | HPGD (0.54) | HPGDEPHX2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL16625022 | 0.75 | HPGD (0.54) | HPGDEPHX2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL3914202 | 0.75 | HPGD (0.54) | HPGDEPHX2CYP2D6CYP2C19 | |
| SCHEMBL9570167 | 0.75 | HPGD (0.54) | HPGDEPHX2CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL21786998 | 0.73 | HPGD (0.53) | HPGDEPHX2CYP1A2CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019114666-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-06-20 | — | — | WO | disclosed |